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The American Journal of Psychiatry, VOL. 142, No. 6

REGULAR ARTICLES | June 01, 1985

Monoamine oxidase inhibitors as treatment for depressed patients with primary degenerative dementia (Alzheimer's disease)

Am J Psychiatry 1985;142:763-764.

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Abstract

Two Alzheimer's patients with disabling depression failed to respond to standard antidepressants but improved with a monoamine oxidase inhibitor. The author points out that the cholinergic system is involved in Alzheimer's symptoms and that demented patients have high monoamine oxidase levels.

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