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The American Journal of Psychiatry, VOL. 141, No. 12

REGULAR ARTICLES | December 01, 1984

Clonidine in the treatment of mania and mixed bipolar disorder

Am J Psychiatry 1984;141:1617-1618.

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Abstract

The symptoms of three bipolar patients remitted after clonidine treatment. One patient presented with mixed bipolar disorder, two were manic, and all were psychotic. One patient's akathisia also appeared to respond to clonidine. Clonidine's thymoleptic effect paralleled resulting cardiovascular changes.

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