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The American Journal of Psychiatry, VOL. 141, No. 10

REGULAR ARTICLES | October 01, 1984

Lithium and tryptophan augmentation in clomipramine-resistant obsessive- compulsive disorder

Am J Psychiatry 1984;141:1283-1285.

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Abstract

Obsessive-compulsive patients with symptoms resistant to clomipramine were treated by lithium or L-tryptophan augmentation. The improvement noted supports the hypothesis that increasing serotonergic neurotransmission ameliorates obsessive symptoms.

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