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The dexamethasone suppression test in hospitalized prepubertal depressed children

Published Online:https://doi.org/10.1176/ajp.141.2.290

The dexamethasone suppression test was performed on 20 hospitalized prepubertal children who met DSM-III criteria for major depressive disorder. Fourteen children (70%) did not suppress cortisol secretion at either 8:00 a.m. or 4:00 p.m. The 4:00 p.m. value alone predicted 93% of the nonsuppressors.

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