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Case report of a toxic reaction from a combination of tryptophan and phenelzine

Published Online:https://doi.org/10.1176/ajp.141.2.281

The addition of tryptophan to a monoamine oxidase inhibitor (MAOI) has been recommended for patients failing to respond to an MAOI alone. The authors report acute behavioral and neurologic toxicity immediately after tryptophan administration in a patient taking phenelzine.

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