Of 41 children, adolescents, and young adults who were withdrawn from
chronic neuroleptic treatment, 18 developed tardive dyskinesia, withdrawal
dyskinesia, nondyskinetic withdrawal symptoms, or transient behavior
deterioration. Development of neuroleptic-related problems seemed to be
associated with cumulative neuroleptic dose and possibly with the sex of
the subject. Only 12 of the 41 subjects required resumption of neuroleptic
treatment after a prolonged trial withdrawal period.