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Case report of carpal tunnel syndrome associated with tranylcypromine

Published Online:https://doi.org/10.1176/ajp.140.9.1229

A man who developed carpal tunnel syndrome while taking tranylcypromine was treated with 300 mg/day of pyridoxine, which resulted in significant improvement. The authors discuss the two major mechanisms by which monoamine oxidase inhibitors can inactivate pyridoxine.

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