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The American Journal of Psychiatry, VOL. 140, No. 8

REGULAR ARTICLES | August 01, 1983

Effect of lithium therapy on glomerular filtration rate

Am J Psychiatry 1983;140:1065-1067.

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Abstract

Patients taking lithium had a slightly higher serum creatinine concentration than controls. Creatinine concentration was independent of lithium level or therapy length, suggesting that lithium decreases glomerular filtration but that this effect is small, noncumulative, and of marginal clinical significance.

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