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Reversal by bethanechol of sexual dysfunction caused by anticholinergic antidepressants

Published Online:https://doi.org/10.1176/ajp.139.9.1193

The anticholinergic properties of currently available antidepressants sometimes cause sexual dysfunction. Bethanechol, a cholinergic drug, was found to give total relief of impotence in two men and of anorgasmy in one woman; none of the subjects suffered side effects.

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