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Loxapine as an alternative to phenothiazines in a case of oculocutaneous skin pigmentation

Published Online:https://doi.org/10.1176/ajp.138.12.1631

The authors describe a patient with changes in oculocutaneous pigmentation that cleared after chlorpromazine was discontinued. They suggest that loxapine may be a suitable alternative to phenothiazines when skin pigmentation and ocular involvement occur, although the patient must be carefully monitored for ocular problems.

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