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"On-off" syndrome treated with lithium carbonate: a case report
Am J Psychiatry 1981;138:1626-1627.
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Abstract

The authors describe a 42-year-old man who developed "on-off" episodes and for whom lithium carbonate proved an effective treatment. They speculate that the predominant effect of lithium in the "on-off" syndrome is to prevent L-dopa desensitization of the dopamine receptor.

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