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Mania associated with LSD ingestion

Published Online:https://doi.org/10.1176/ajp.138.11.1508

The authors report a patient who suffered a full-blown manic attack after ingesting LSD or an LSD analogue. The patient experienced acute symptoms of LSD intoxication, which resolved but were followed in about 3 weeks by a typical manic episode of psychotic magnitude. The mania cleared with lithium therapy.

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