The authors gave 22 chemical workers neurological, psychiatric, and
neuropsychological examinations and placed them in one of two groups
according to their degree of exposure to trimethyltin chloride spillage
during January 1978. Other chemicals to which they had been exposed were
dimethyltin dichloride and methyl chloride. Specific and nonspecific
symptoms of intoxication of the CNS showed a significantly greater
frequency in the highly exposed group, including cycles of depression and
destructive rage, each lasting a few hours. These observations should alert
diagnosticians to this type of occupational exposure.
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