The author reviews studies of the development and scientific
exploitation of two true-breeding strains of pointer dogs, one of which is
basically normal and one of which is nervous, particularly around people.
Basic studies, which generally contrast the nervous dogs with the normal
dogs, include studies of inheritance, early experience, conditioning,
psychophysiology, neuropharmacology, and neurochemistry. The author
suggests that the nervous line is an animal model of human psychopathology
and probably of cardiac pathology.