Lithium treatment has been associated with a wide range of cardiac
complications. The authors report three additional cases of cardiac sinus
node dysfunction due to lithium. Two of the three cases were documented to
be lithium dependent by the use of Holter monitoring of cardiac rhythm. On
the basis of this finding as well as other reports in the literature the
authors recommend careful monitoring of the pulse of patients taking
lithium as well as ECG monitoring of patients who are over the age of 50 or
who have a history of cardiac disease.