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The American Journal of Psychiatry, VOL. 136, No. 3

REGULAR ARTICLES | March 01, 1979

Phenylethylamine in rhesus monkeys: interactions with alpha-methyl-para- tyrosine and l-dopa

Am J Psychiatry 1979;136:311-313.

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Abstract

Rhesus monkeys, pretreated with alpha-methyl-para-tryosine (AMPT) and subsequently injected with phenylethylamine (PEA), did not demonstrate the characteristic amphetamine-like PEA effects. However, when AMPT pretreatment was followed with l-dopa and then PEA injection, PEA effects were restored. These results are compatible with a dopamine theory of schizophrenia.

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