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Effect of diet on urinary MHPG excretion in depressed patients and normal control subjects

Published Online:https://doi.org/10.1176/ajp.134.8.914

The authors studied the effect of a catecholamine-controlled diet on the urinary level of 3-methoxy-4-hydroxyphenylglycol (MHPG) of 6 depressed patients and 6 normal volunteers. The normal subjects showed no change in MHPG levels on or off the diet; the depressed patients showed a significant increase in MHPG while off the diet.

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