The authors found a 60% incidence of difficulties in sexual functioning
in 57 male patients who had taken thioridazine. Ejaculatory problems were
the most frequent dysfunction; a third of these patients experienced
retrograde ejaculation. The incidence of sexual difficulties in 64 patients
who had taken other major tranquilizers was only 25%. None of the latter
group experienced retrograde ejaculation- most had difficulty achieving and
maintaining erection. The authors recommend consideration of the
possibility of sexual dysfunction in patients given thioridazine.