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The American Journal of Psychiatry, VOL. 132, No. 11

REGULAR ARTICLES | November 01, 1975

The use of bethanechol chloride with tricyclic antidepressants

Am J Psychiatry 1975;132:1202-1204.

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Abstract

The author describes the use of bethanechol chloride to relieve side effects, including salivary inactivation, constipation, and bladder inhibition, which result from the anticholinergic action of tricyclic antidepressants. He suggests that the use of cholinergic medication during antidepressant therapy may extend the use of the tricyclics to patients who find anticholinergic side effects especially troublesome.

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