A 57-year-old man with no personal or family history of manic-
depressive disease developed symptoms of hypomania after a cerebrovascular
accident and surgical trauma to the brain. The patient responded well to
lithium carbonate treatment over a 2-year period. Although this therapy is
contraindicated in cases of organic brain syndrome, the authors suggest
that it should be considered in the management of hypomanic behavior
following organic brain dysfunction.