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Mesoridazine Versus Chlorpromazine in Acute Schizophrenia: A Double-Blind Investigation
T. A. HAMID; WILLIAM J. WERTZ
Am J Psychiatry 1973;130:689-692.
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16 Nile St., Giza, Egypt, U.A.R.

Superintendent, Detroit Psychiatric Institute, 1151 Taylor St., Detroit, Mich. 48202

1973, The American Psychiatric Association

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Abstract

A double-blind comparison of mesoridazine and chlorpromazine with 91 newly admitted, acutely psychotic patients showed that symptoms grouped in the following composites improved significantly more in the mesoridazine patients than in the chlorpromazine patients: motor activity, attitude and behavior, emotional response, and ideation and thought processes. The mesoridazine patients experienced less sedation than the chlorpromazine patients.

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