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The American Journal of Psychiatry, VOL. 130, No. 5

Articles | May 01, 1973

The 24-Hour Serum Lithium Level as a Prognosticator of Dosage Requirements

THOMAS B. COOPER; PER-ERICK E. BERGNER; GEORGE M. SIMPSON

Am J Psychiatry 1973;130:601-603.

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Chief Investigators, Research Center, Rockland State Hospital, Orangeburg, N.Y. 10962

Principal Research Psychiatrist, Research Center, Rockland State Hospital, Orangeburg, N.Y. 10962

1973, The American Psychiatric Association

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Abstract

A technique is described that enables a physician to determine a patient's lithium dosage requirement on the basis of a single blood sample collected 24 hours after the administration of a 600 mg. priming dose of lithium. The authors discuss the basis of this technique and emphasize the importance of ascertaining that the patient has ingested the priming dose of lithium.

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