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The American Journal of Psychiatry, VOL. 126, No. 7

Articles | January 01, 1970

Treatment of Mania with Cinanserin, an Antiserotonin Agent

FRANCIS J. KANE, JR.

Am J Psychiatry 1970;126:1020-1023.

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Associate professor of psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C. 27514

1970, American Psychiatric Association

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Abstract

Cinanserin, a new drug with antiserotonin activity, produced a rapid remission of the manic phase of manic-depressive psychosis in five of seven cases described by the author. No significant toxicity was encountered. The findings indicate that this drug deserves further clinical study.

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