The American Psychiatric Association (APA) has updated its Privacy Policy and Terms of Use, including with new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences.

Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.

×
Published Online:https://doi.org/10.1176/ajp.125.10.1358

In this study of the families of 59 manic-depressive, manic type probands, the predominant affective illness among the family members was depression without mania, although mania was frequent. The findings suggest that genetic transmission occurred by a sex-linked single or double dominant gene. In two families affective disorder was linked to color blindness, implying that the X-linked gene for manic-depressive psychosis is on the short arm of the X chromosome.

Access content

To read the fulltext, please use one of the options below to sign in or purchase access.