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A Double-Blind Study of the Effect of Ribonucleic Acid in Senile Brain Disease
JOHN H. NODINE; MARK W. SHULKIN; JOSEPH W. SLAP; MURRAY LEVINE; KENNETH FREIBERG
Am J Psychiatry 1967;123:1257-1259.
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Associate Professor of Medicine, Section of Clinical Pharmacology

Senior Instructor, Department of Psychiatry

Clinical Assistant Professor of Medicine and Psychiatry

Assistant Professor of Psychology, Yale University, New Haven, Conn.

1966-67, American Psychiatric Association

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Abstract

A double-blind study to test the effect of orally administered ribonucleic acid upon the course of senile and arteriosclerotic brain disease failed to confirm the positive findings of other investigators. The authors conclude that RNA administered in this form does not appear to bring about improvement or reversal of senile brain disease.

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