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CLINICAL NOTES   |    
MAO ACTIVITY IN RELATION TO DEPRESSION
AARON FELDSTEIN; HUDSON HOAGLAND; KEITH KAM-KIM WONG; MILAGROS RIVERA OKTEM; HARRY FREEMAN
Am J Psychiatry 1964;120:1192-1194.
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The Worcester Foundation for Experimental Biology, Shrewsbury, Mass., and Medfield State Hospital, Medfield, Mass.

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Abstract

Serotonin-C14 was administered orally to 22 depressed patients and 22 normal subjects. The recovery of 5-HIAA-C14 calculated on the basis of administered serotonin-C14 and adjusted for variations in total carbon-14 recovery showed no significant difference between the groups. It was concluded that MAO and aldehyde de-hydrogenase functioned normally in the depressed patients within the limitations imposed by the method.

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