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The American Journal of Psychiatry, VOL. 120, No. 8

CASE REPORTS | February 01, 1964

AN UNUSUAL REACTION TO COMBINED LIBRIUM-BARBITURATE THERAPY

FRANCIS J. KANE, JR.; ROBERT L. MCCURDY

Am J Psychiatry 1964;120:816-816.

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Dept. of Psychiatry, University of North Carolina, Chapel Hill, N. C.

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Abstract

An unusual syndrome of drowsiness, unsteadiness and fine horizontal nystagmus is reported following the use of chlordiazepoxide and phenobarbital, which remitted upon cessation of barbiturate therapy. This suggests that therapies using more than one drug acting on the C.N.S. should be approached with caution.

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