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The American Journal of Psychiatry, VOL. 119, No. 4

CLINICAL NOTES | October 01, 1962

MASSIVE DOSES OF TRIFLUOPERAZINE IN THE TREATMENT OF COMPULSIVE RITUALS

MILTON ALTSCHULER

Am J Psychiatry 1962;119:367-368.

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Resident Psychiatrist, University of Texas, Galveston, Tex.

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Abstract

1. Five of twelve patients with severe compulsive rituals showed improvement in symptomatology on high doses of trifluoperazine. 2. Blood and urine studies remained stable throughout the study. 3. Minor dystonic side effects were noted that were readily reversible when the drug was decreased or discontinued.

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