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THE EFFECT OF TRI-IODOTHYRONINE ON ABNORMALITIES IN THE CEREBROSPINAL FLUID OF CHRONIC SCHIZOPHRENIC PATIENTS

Published Online:https://doi.org/10.1176/ajp.119.2.170

1. In a group of 27 chronic schizophrenics chosen randomly, abnormalities in the cerebrospinal fluid protein and gold curve were noted.

2. A statistically significant normalizing effect on these indices occurred when the patients were placed on tri-iodothyronine.

3. The relationship of the findings to thyroid function has been discussed elsewhere. Decreased metabolism is presumed to be a relating factor.

4. Further work in this area seems indicated.

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