Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
Am J Psychiatry 1961;118:212-217.
View Author and Article Information

The Departments of Psychiatry and Medicine, University of Pennsylvania, Philadelphia, Pa.

text A A A
PDF of the full text article.

New physiological discoveries are providing the behavioral sciences with a unique opportunity for the reconstruction of traditional theories of motivation. We are no longer constrained, for example, to view overeating solely as a result of an increased hunger drive. This apparent contradiction results from the demonstration that the hypothalamic centers mediating hunger and satiety have separate anatomical localizations and separable behavioral consequences. Overeating can thus theoretically result either from an increase in hunger drive or from an decrease in satiability. The first possibility has generally been accepted with little question. The second has now been demonstrated by experimental damage to the satiety centers of animals who thereupon present the paradox of an animal which eats itself into obesity through a hunger drive which is actually reduced in intensity. Recent clinical studies suggest that either decreased satiability or increased drive may occur in human obesity. Persons manifesting the "night-eating syndrome" report an inability to stop eating rather than any increased desire to eat. Obese persons who overeat in binges, on the other hand, report compelling urges to overeat at such times.

Abstract Teaser
Figures in this Article


hunger ; satiation
Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).




CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe

Web of Science® Times Cited: 17

Related Content
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 50.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 25.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 25.  >
The American Psychiatric Publishing Textbook of Psychiatry, 5th Edition > Chapter 23.  >
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 48.  >
Topic Collections
Psychiatric News
PubMed Articles