0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
COMPARATIVE CLINICAL EXPERIENCE WITH FIVE ANTIDEPRESSANTS
JOHN P. HOLT; ELEANORE R. WRIGHT; ARTHUR O. HECKER
Am J Psychiatry 1960;117:533-538.
View Author and Article Information

Embreeville State Hospital, Embreeville, Pa.

text A A A
PDF of the full text article.
Abstract

Based on our results, we feel that all 5 of the antidepressants are effective agents and are generally superior to the amphetamines and phenothiazines in producing remission or relief of primary and secondary symptoms which comprise the depressive syndrome. Generally, the best response to the antidepressants occurs in patients with primary depressive reactions. Most patients with depressive features associated with schizophrenia or organic brain disorders experience significant improvement in depressive symptomatology without experienceNo serious complications or side effects were produced by the drugs. Postural hypotension, excessive psychomotor stimulation and aggravation of schizophrenic symptomatology were the most bothersome side effects and it would appear that each drug has a similar capacity to cause these reactions. Neither hemopoietic nor hepatic toxicity was evidenced during our experience with the drugs.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
 
Username
Password
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

+

References

+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Web of Science® Times Cited: 15

Related Content
Articles
Books
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 2.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 2.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 1.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 3.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 3.  >
Topic Collections
Psychiatric News
Read more at Psychiatric News >>
APA Guidelines
PubMed Articles