0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

CLINICAL NOTES   |    
IMIPRAMINE THERAPY OF DEPRESSIVE SYNDROMES
LEON REZNIKOFF
Am J Psychiatry 1960;116:1110-1111.
View Author and Article Information

Clinical Director, Hudson County Hospital for Mental Diseases, Secaucus, N. J.

text A A A
PDF of the full text article.
Abstract

Forty patients suffering from various depressive syndromes had been treated with imipramine hydrochloride for a period of 3 to 12 months.Remissions and marked improvement had been obtained in 80% of cases.The effect of the drug is apparent in 2 to 4 weeks after beginning of therapy, and in some cases it is noticeable even after a few days.Imipramine is effective regardless of long duration of the depression. The relief of depressive feelings is not dramatic and sudden, as with ECT, but rather gradual.In refractory patients with a tendency to relapse, the drug had been administered in reduced dosage for 12 months, and apparently can be continued indefinitely; this is a distinct advantage over ECT, since ambulatory patients inevitably after a few courses of ECT resist further attempts at maintenance, or preventive ECT.In none of the 40 patients did imipramine have to be discontinued because of side effects, although several patients complained of dryness of the mouth, profuse perspiration, constipation, dizziness, blurred vision and hot flushes.

Abstract Teaser
Figures in this Article

Topics

syndrome ; imipramine
Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
 
Username
Password
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

+

References

+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Web of Science® Times Cited: 5

Related Content
Articles
Books
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 1.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 12.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 12.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 12.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 12.  >
Topic Collections
Psychiatric News
PubMed Articles