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CLINICAL NOTES   |    
IPRONIAZID (MARSILID): ITS USE IN OFFICE TREATMENT OF DEPRESSION
WILSON G. SCANLON; WILLIAM M. WHITE
Am J Psychiatry 1958;114:1036-1037.
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Silver Hill Foundation for the Treatment of the Psychoneuroses, New Canaan, Conn.

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Abstract

1. Judicious management of the iproniazid dosage and of the patient's activities so as to prevent syncope, makes usage of the drug safer, avoids the majority of reported adverse side-effects, and still provides the blood stream and spinal fluid with a sufficient titer to produce a salutary effect on mood.2. It is our impression that iproniazid is most effective and produces fewer side-effects in cases of uncomplicated depression.3. The rapid and sustained response of the patients who required ECT suggests that ECT and iproniazid are synergistic.

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