1. Judicious management of the iproniazid dosage and of the patient's activities so as to prevent syncope, makes usage of the drug safer, avoids the majority of reported adverse side-effects, and still provides the blood stream and spinal fluid with a sufficient titer to produce a salutary effect on mood.2. It is our impression that iproniazid is most effective and produces fewer side-effects in cases of uncomplicated depression.3. The rapid and sustained response of the patients who required ECT suggests that ECT and iproniazid are synergistic.
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