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The American Journal of Psychiatry, VOL. 107, No. 4

Article | October 01, 1950

NONCONVULSIVE ELECTRIC STIMULATION THERAPY Its place in the Treatement of Affective Disorders, with Notes on the Reciprocal Relationship of Anxiety and Depression

LEO ALEXANDER

Am J Psychiatry 1950;107:241-250.

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Director, Neurobiologic Unit, Division of Psychiatric Research, Boston State Hospital; Instructor in Psychiatry, Tufts College Medical School.

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Abstract

Convulsive treatment through frontal leads inhibits respiration temporarily; nonconvulsive treatment through frontal or temporopariental leads stimulates respiration.Convulsive treatment through frontal leads relieves depression but reduces awareness for memory content and may enhance anxiety, while nonconvulsive treatment through temporoparietal leads relieves anxiety and restores awareness for memory content, but may enhance depression. By using both, it is possible to avoid the "untreatable" residual after electroshock treatment.

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