Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
PREFRONTAL LOBOTOMY A Preliminary Appraisal of the Behavioral Results
Am J Psychiatry 1946;103:217-228.
View Author and Article Information

The Division of Psychiatry, Department of Medicine, The University of Chicago.

The Department of Psychiatry, University of Illinois College of Medicine.

The Department of Neurology, The Illinois Neuropsychiatric Institute.

text A A A
PDF of the full text article.

In a preliminary investigation, an impairment index scale developed by one of us (W.C.H.) for reflecting impairment of biological intelligence has been applied to 8 carefully selected individuals before and after prefrontal lobotomy and to another individual following lobotomy. Several of these cases were found to exhibit an impairment of biological intelligence prior to lobotomy. This operation did not consistently alter the degree of impairment manifested quantitatively in contrast with high impairment scores obtained for frontal lobectomies. This would seem to point to the cortex of the frontal lobes as the region of the brain in which the functions reflected by the impairment index are maximally represented or localized.It is concluded that:1. Impaired biological intelligence, as encountered in some forms of psychopathy, is not relieved by the operation known as prefrontal lobotomy.2. Lobotomy may not increase the degree of impairment of this function. [See Fig. 2 In Source Pdf].3. Little is known concerning the behavioral effects of prefrontal lobotomy.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).




CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe

Web of Science® Times Cited: 31

Related Content
The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th Edition > Chapter 7.  >
Textbook of Traumatic Brain Injury, 2nd Edition > Chapter 8.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 51.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 16.  >
Gabbard's Treatments of Psychiatric Disorders, 4th Edition > Chapter 12.  >
Topic Collections
Psychiatric News
PubMed Articles