0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
SELF-INDUCED PSYCHOSIS WITH HYPERTHYROIDISM COMPLICATING MANIC DEPRESSIVE PSYCHOSIS Experimental Human Hyperthyroidism
GEORGE N. THOMPSON
Am J Psychiatry 1945;102:395-398.
View Author and Article Information

The Department of Psychiatry of the Los Angeles General Hospital and the School of Medicine, University of Southern California.

text A A A
PDF of the full text article.
Abstract

A patient suffering with manic-depressive psychosis, depressed type, the diagnosis being based upon the history of repeated cyclothymic depressions with typical symptomatology and complete recoveries with remissions free from symptoms, attempted during a depression to commit suicide so that it would be unrecognized as such. Massive, prolonged thyroid overdosage extending over a period of 1½ years resulted in a clinical picture of hyperthyroidism indistinguishable from typical Grave's disease. A marked increase in the overdosage resulted in the clinical picture of psychosis with hyperthyroidism. Removal of the drug resulted in the remission of symptoms due to thyroid toxicity, the clinical picture of a retarded depression remaining. Recovery from the depression followed a period of several months' hospitalization under psychiatric régime. During the acute toxicity the superimposed psychosis sufficiently masked the depression that it was not detected. This unusual method of attempted suicide provided opportunity to study the physiologic effects of massive, prolonged thyroid overdosage—a case of experimental human hyperthyroidism.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
 
Username
Password
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

+

References

+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Web of Science® Times Cited: 2

Related Content
Articles
Books
The American Psychiatric Publishing Textbook of Psychiatry, 5th Edition > Chapter 11.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 62.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 62.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 19.  >
Manual of Clinical Psychopharmacology, 7th Edition > Chapter 1.  >
Topic Collections
Psychiatric News
APA Guidelines
PubMed Articles