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EFFECT OF BENZEDRINE SULPHATE ALTERNATED WITH SODIUM AMYTAL IN SCHIZOPHRENIA
LEON REZNIKOFF
Am J Psychiatry 1941;98:196-200.
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Clinical Director, Hudson County Hospital for Mental Diseases, Secaucus, N. J.

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Abstract

1. Administration of benzedrine sulphate and sodium amytal on alternating days cannot be recommended as a therapeutic procedure for schizophrenia.2. While the author is not enthusiastic about results obtainable with metrazol shock therapy in schizophrenia because of the definitely temporary nature of improvement when it does occur, and the serious complications, the results obtained from the trial with benzedrine and amytal, when compared with metrazol shock, were not only considerably inferior but practically negligible.3. Intravenous injections of large doses of benzedrine sulphate (30 mg.) every other day for a month to young, physically healthy adults caused no harmful effects of permanent nature.

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