In five clinically and serologically typical cases of dementia paralytica, there developed features strongly suggestive of manic-depressive or schizophrenic psychoses.Long-section studies of the cases pointed to the conclusion that these features were not merely a part of the neurosyphilitic disease but were manifestations of true manic-depressive and Schizophrenic psychoses which pursued their own lines of development independent of the organic disease. Anatomic observations available in one case supported this view.It is believed that manic-depressive or schizophrenic psychoses accompany dementia paralytica too frequently to be regarded as accidental concomitants of the latter. Apparently they are directly provoked by the organic brain disease.
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