The psychological reactions of 30 behavior problem children who received benzedrine sulfate for one week were observed. There was a spectacular improvement in school performance in half of the children. A large proportion of the patients became emotionally subdued without, however, losing interest in their surroundings. A variety of other definite behavior changes were also noted. Dosage, unfavorable responses, and duration of effect of the drug are discussed, and it is suggested that its use in the treatment of children with behavior disorders be supervised by physicians trained in child psychiatry.