Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Article   |    
Howard D. McIntyre
Am J Psychiatry 1928;84:919-943.
text A A A
PDF of the full text article.

1. Blood chemical examinations are of great value in the study of the early stages of mental disease especially those psychoses showing any symptoms of hallucinatory confusion. They assist in the differential diagnosis of the toxic psychoses especially of those on a uremic basis. They also aid in demonstrating the role of toxic factors in precipitating psychotic attacks in the major psychoses.2. Evidence is presented to show that manic-depressive, schizoid and confusional reactions may in their early stages be accompanied by signs of toxemia, viz., leukocytosis, acidosis, fever and nitrogen retention.3. Treatment directed toward the elimination of the toxemia is frequently effective in bringing about a mental recovery.4. The toxins, acid or otherwise, so affect the hydrated colloids of the nerve cells as to bring about a cracking of the emulsion of which the nerve cell is composed. Treatment to be effective must take place before this irreversible cracking point is reached.

Abstract Teaser
Figures in this Article

Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).




CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe

Related Content
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition > Chapter 0.  >
DSM-5™ Clinical Cases > Chapter 2.  >
DSM-5™ Clinical Cases > Chapter 2.  >
DSM-5™ Clinical Cases > Chapter 17.  >
DSM-5™ Clinical Cases > Chapter 2.  >
Topic Collections
Psychiatric News
PubMed Articles
Psychiatric adverse effects of pediatric corticosteroid use. Mayo Clin Proc 2014;89(6):817-34.doi:10.1016/j.mayocp.2014.01.010.
Bath Salts Abuse leading to New Onset Psychosis and Potential for Violence. Clin Schizophr Relat Psychoses 2014;():1-14.doi:10.3371/CSRP.JORO.061314.