(1) The essence of the manic-depressive reactions is the occurrence of some appropriate affective attitude of the organism as a whole which is of purposeful character, abnormal because of its severity and duration and because there is no apparent external cause for its adoption.(2) The so-called mixed states and atypical forms are not mixtures simply of certain traits but represent affective oscillations colored by peculiarities in the make-up of the individual patient. Such modes of adjustment must be carefully studied and weighed in rendering a prognosis in any individual case.
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