Impairments in learning-dependent predictive perception (11–14) in young people may lead to isolation and psychosis. The hierarchical model of temporal processing (15) suggests that previous evolutionary and individual experience shape the manner by which neural circuitry stores memories and provides context for predicting perception. In each moment, the process of learning about relationships, whether between percepts, between people, or between adjacent units of time, helps us predict what will happen next. We are dependent on this system for everything from survival to joy. When it does not function well, the resultant confusion and discouragement lead to a dampening of emotional and cognitive connections with others, and a more personal and idiosyncratic set of interpretations of the outside world begins to gain prominence. The Strauss and Gold data suggest that people with schizophrenia have a weakened tendency to be optimistic about future events. This may render them vulnerable to having their expectations about their experience of the external world overwhelmed by internally based biases. If I can't understand how you feel, I won't be able to predict what you will do, which may make being with you less enjoyable to me. If I can't understand how I feel or what in the world will make me happy, the path of least resistance may circle me back to a resting point of externally incorrect but internally rewarding thoughts and fantasies. As with all Hebbian models of healthy neuroplasticity (16), the more this path is engaged, the more solidified it will become. Odd interpretations well worn and untested develop into delusional beliefs; a system that rewards an internally directed focus enlivens thoughts to hallucinations.