Abatement of alcohol dependence among American Indians from eight reservations was associated with female sex, older age, marriage, earlier onset of dependence, and self-reported depressive symptoms from drinking. Gilder et al. (p. 1172) also found that the percentage of Native American heritage, severity of dependence, and treatment were not related to remission. Of the 580 participants surveyed, 254 met the criteria for lifetime alcohol dependence. However, the 59% remission rate within this subgroup was comparable to rates in national samples. Dr. Joseph Westermeyer comments on this high-risk population in an editorial on p. 1093.