Two large twin studies demonstrate genetic overlap between certain anxiety disorders and personality characteristics. In fact, Bienvenu et al. (p. 1714) found that the genetic influence on introversion and neuroticism accounted entirely for the genetic liability to social phobia and agoraphobia, but not animal phobia. Among 7,800 twins from monozygotic and dizygotic pairs, environmental effects shared by twins did not contribute to the correlations of introversion and neuroticism with phobias, and unique experiences had modest correlations. Commonality between social phobia and avoidant personality disorder was demonstrated by Reichborn-Kjennerud et al. (p. 1722). Their study of 1,427 twins in monozygotic and dizygotic pairs indicated that the two disorders are influenced by the same genetic factors. Environmental factors unique to each twin also had substantial effects, but the environmental influences on the two disorders were uncorrelated. The implications of these findings are reviewed in an editorial by Dr. Jordan Smoller on p. 1631.