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Clinical Case Conference   |    
Management of Clozapine-Induced Fever in a Child
David I. Driver, M.D.; Afsoon A. Anvari, B.S.; Christina M. Peroutka, M.D.; Rachna Kataria; Jerry Overman, Pharm.D., B.C.P.P.; David Lang, M.D.; Maria Tietcheu, B.S.N.; Reggie Parker, B.S.N.; Keith Baptiste, B.S.N.; Judith L. Rapoport, M.D.; Nitin Gogtay, M.D.
Am J Psychiatry 2014;171:398-402. doi:10.1176/appi.ajp.2013.13070866
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The authors report no financial relationships with commercial interests.

From the Child Psychiatry Branch, NIMH, Bethesda, Md.

Address correspondence to Dr. Driver (davididriver@gmail.com).

Copyright © 2014 by the American Psychiatric Association

Received July 05, 2013; Revised September 30, 2013; Accepted November 01, 2013.

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FIGURE 1. Plot of Clozapine Dosage and Body Temperature Over Time in an 11-Year-Old Girl With Childhood-Onset Schizophrenia Treated With Clozapine
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TABLE 1.Summary of a Literature Review on Fever and Clozapine Usea
Table Footer Note

a N/A=not available.

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TABLE 2.Chart for Differential Diagnosis for Fever in Clozapine Use
Table Footer Note

a Can be elevated in the context of psychotic agitation (<1000 U/L).

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