However, an unfortunate limitation of the published report from Oquendo et al. is the lack of hazard ratios or other measures of effect size. Such information would be valuable, despite the lack of statistical power, because even underpowered findings are important to incorporate in later meta-analyses. In addition, the Oquendo et al. study is the first trial comparing lithium and valproate with a primary outcome of suicidal behavior, and even an underpowered finding would help inform future research. While it is also true that assumptions concerning proportional hazards may not be met for this study, given the intersection of survival curves in Figure 2, this can sometimes be addressed by breaking the curves into shorter time frames. We would like to request that the authors provide, if possible, hazard ratios or another measure of effect size for their reported outcomes, especially the time to first suicide attempt (since examining suicidal behavior alone, rather than outcomes including prophylactic hospitalizations, has previously been a more sensitive measure for detecting differences in suicidal behavior among medications ).