Significant differences were observed in both Liebowitz Social Anxiety Scale symptom levels and Sheehan Disability Scale scores between patients receiving augmentation with clonazepam and patients continuing with sertraline alone. The venlafaxine-treated patients had an intermediate outcome, with their symptom and disability scores not significantly different from either of the other two groups, although outcomes were closer to the sertraline group. The overall patient response rates are instructive: 27% with clonazepam, 19% with venlafaxine, and 17% with sertraline plus placebo. Merely waiting an additional 10 weeks and continuing sertraline produced an additional 17% of responders, much greater than the 10% margin of effect between clonazepam and sertraline plus placebo. While a number of studies in anxiety disorder patients have shown that longer duration of treatment with SSRIs will yield additional responders (5, 6), this fact is often overlooked by clinicians pressured to provide more or different medications to anxious patients who are frustrated with their lack of short-term response. The limited difference between the two antidepressants is also noteworthy and suggests that switching to a different antidepressant class is less effective than augmenting with a benzodiazepine. While some may argue that higher doses of venlafaxine could have achieved greater effect (the mean doses were 168 mg), this notion is thought to be more relevant for the treatment of depression (many anxiety disorder experts feel that higher doses of SNRIs are anxiogenic because of greater noradrenergic effects at these levels). The clonazepam group, compared with the other two groups, had numerically fewer adverse events, except for somnolence, in multiple categories. Hence, this strategy was both more effective and probably more tolerable. The incidence of insomnia was markedly lower in the clonazepam group (13% compared with 42% and 36%), which is instructive in light of recent evidence that insomnia seems to predict poor response to CBT in social anxiety (7).