To the Editor: Selective serotonin reuptake inhibiting (SSRI) antidepressants commonly produce iatrogenic sexual dysfunction (1, 2). It is uncommon for spontaneous remission of this side effect to occur, even after taking the SSRI for years (3). A variety of augmentation strategies have been proposed to reverse SSRI-induced sexual dysfunction (4). Sildenafil has been used to reverse SSRI-induced anorgasmia in a woman (5). Vardenafil, a phosphodiesterase type-5 inhibitor, is indicated in the treatment of male erectile disorder. I report here a case of SSRI-induced anorgasmia in a woman that was reversed by vardenafil.