In 1999, APA and NIMH convened the first DSM-V research planning conference, where areas of research importance were identified for the field. Five areas were identified as essential: 1) developmental issues, 2) gaps in the current system, 3) disability and impairment, 4) neurosciences, and 5) nomenclature. In 2000, the chairs of the five work groups in these areas held another conference to define the work process for the white papers represented in this book. Liaisons with NIMH, the National Institute on Drug Abuse, and the National Institute on Alcohol and Alcohol Abuse were established. Also in 2000, a third conference was held, and a cross-cultural work group was added. Subsequently, this volume’s six chapters were produced by these working groups. I should add that, in my opinion, the addition of the work group on cross-cultural psychiatry was a much-needed and beneficial step for the field at large.