According to AmeriChoice’s interpretation of these guidelines, we "shalt not" combine atypical antipsychotics until we first use clozapine. I do not believe that this commandment is rational or therapeutic for a certain group of patients. These are the patients who have a significant but partial response, with minimal or no side effects, to the maximum dose of an atypical antipsychotic. For example, before medication, these patients might have intrusive auditory hallucinations constantly or almost every day. After taking the maximum dose of an atypical antipsychotic, they might have less intrusive auditory hallucinations that occur only 1 or 2 days a week.